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Finasteride plus Minoxidil – effective baldness medication
Finasteride-based preparations – Propecia, Fincar, Finpecia, Proscar. Preparations with Minoxidil – Rogaine.
Finasteride (Propecia) is used in the treatment and prevention of male-pattern hair loss.
Testosterone, having interacted with the enzyme 5α-reductase, turns into dihydrotestosterone (DHT), which is involved in the development of androgenetic alopecia. Male pattern baldness is caused by the action of DHT, which causes the hair follicles to shrink or miniaturize. Finasteride is highly effective in reducing the concentration of DHT in both blood plasma and prostate tissue. Finasteride is one of the FDA-approved treatments for male hair loss.
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Finasteride is the most effective treatment for alopecia, but in areas where hair follicles are still preserved. The main advantage of this device is the ability to maintain the growth of the patient’s own hair or significantly slow down the progressive hair loss associated with androgenic alopecia.
Finasteride is also used to treat benign prostatic hyperplasia. Suppression of DHT formation is accompanied by a decrease in the size of the prostate gland, an increase in the maximum urinary rate and a decrease in the severity of symptoms associated with prostatic hyperplasia.
The goal is to increase the growth of your own hair. Finasteride helps to reduce hair miniaturization, thereby increasing the volume of your own hair and improving its quality.
The graph below shows that the maximum improvement from taking finasteride is expected, on average, after one year of use. The results will last for about 2-3 years, then the effect will decrease again. Finasteride has also been tested for hair loss in women; but the results were no better than the placebo.
According to the results of numerous studies, taking finasteride has led to a decrease in the loss of their own hair in patients with diagnosed androgenic alopecia. Also, studies have shown that this drug does not work for everyone. The assessment of the condition of hair quality and the need for further use of finasteride is determined by your doctor. The duration of use depends on the duration of use of finasteride. If you stop using it, you can lose your previously restored hair within about 12 months. We must remember the role that finastreide plays in blocking the formation of dihydrotestosterone. When finasteride is canceled, this hormone will again begin its destructive effect on the hair.
Preventing Shock Loss – Hair transplant is a stressful situation for a person. To minimize the loss of shock, we recommend applying finasteride 2 weeks before hair transplant. For optimal results, it is advisable to continue using it for at least 6 months after the hair transplant.
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How Finasteride works
The mechanism of action of finasteride is based on the specific competitive effect of type II 5-alpha reductase, an intracellular enzyme that converts testosterone into the more active androgen, dihydrotestosterone (DHT). In BPH, its increase depends on the conversion of testosterone to dihydrotestosterone in the prostate. Simply put, finasteride disrupts the conversion of testosterone into the more potent form of DHT. Decreased serum and tissue DHT concentrations result in less adverse effects on hair follicles. As a result, the interruption of DHT formation plays a key role in stopping the development of androgenic alopecia in men.
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Finasteride reviews – when will hair grow back?
Finasteride quickly begins to block the formation of dihydrotestosterone (DHT) after the start of use, but it takes time for hair to start growing. It must be remembered that healthy hair grows an average of one centimeter per month, so it takes time to see visible improvement. According to the results of clinical studies, it is necessary to take finasteride daily for 3 months or more to see the effect. After 6 months after application, you can notice the newly growing hair in exchange for the lost hair and it will look not just like fluff, but like real hair. If finasteride has not worked within 12 months, its further use is most likely inappropriate.
A visible improvement was seen in 40-50% of cases. Microscopic improvement was observed in patients after the first months of use. It is necessary to assess the effect of finasteride using microscopic assessment.
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The typical dose of finasteride for hair loss treatment is 1 mg per day. Finasteride is also available in a 5 mg tablet called Proscar. Some patients divided the pill into several parts, bringing the dosage closer to the dosage of Finasteride, since this came out more economically. The absorption of finasteride from the gastrointestinal tract is completed within 6-8 hours after ingestion.
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Regaine (Minoxidil) – reviews
I noticed the effect of Regaine after about 3 weeks of taking the drug. Hair began to fall out less, the bulbs became denser. The general condition of the hair has not changed. there was no glitter, nothing else.
After 5 weeks after taking the drug, the result was on the face, the hair really began to fall out less, the hair structure, as it seemed to me, became a little thicker. But about 1.5 months later, I again encountered this problem. Hair began to fall out again. Normally, experts today say 60-100 hairs per day are allowed. I probably fit into this figure well, maybe a little more. But when I was counting 60 per day in my mind, 1800 per month, you can stay without hair at all)).
A noticeable effect occurs after about 3-4 months of regular use of the product. But this treatment is not cheap.
The drug is sold in pharmacies in three types: 2% and 5% lotion, as well as 5% foam, the latter was not available at the time of purchase.
To summarize, Regaine did not make much of an impression on me. Its effect is tangible, but temporary. It costs no less than Vichy ampoules, even a little more. For me, I would rather buy another pack of ampoules and use them to carry out prophylaxis.
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Regaine – when will your hair be restored?
It takes a certain time for hair loss to stop and new ones appear in place of the hair loss. In men and women, the rate of onset of noticeable changes is somewhat different. With regular use of foam 2 times a day in men, the first results of treatment can be seen in 2-4 months, and in women who need to use the drug once a day – within 3-6 months1.
Initially, the restored hair is thin, similar to vellus hair. With the activation of the follicles, an increase in hair growth is observed under the condition of constant use of the drug2.
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