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Clomid is a drug for the treatment of infertility, used to diagnose violations of the gonadotropic function of the pituitary gland. Clomid is an active ingredient. The active ingredient of the drug is clomiphene. Clomiphene belongs to antiestrogenic agents, selectively blocks receptor binding of estradiol in the ovaries and hypothalamus. This leads to inhibition of negative feedback, stimulates ovulation and the production of gonadotropins.


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Clomid is an non-steroid anti-estrogen. Mechanism of its action consists in a specific binding with receptor for estrogen in ovary and hypophis. In patients with low estrogen levels in organism it causes estrogen effect and in ones with high estrogen levels it causes anti-estrogen effect. Its small doses increase secretion of gonadotropins (prolactin, Follicle stimulating hormone, FSH and interstitial cell-stimulating hormone), stimulates ovulation; in large doses slows secretion of gonadotropins. In the whole action of Clomid consists in stimulation of ovulation to occur and prepares the body for pregnancy.

This medication may be used for male patients with infertility caused by low production of sperm.Clomid is administered to stimulate ovulation 50 mg 1 time a day at bedtime, starting from 5th day of the menstrual cycle during 5 days (in the absence of the cycle - at any time). In case of no effect (ovulation does not occur within 30 days) increase the dose to 150 mg / day or lengthen the course to 10 days.

Take exactly as prescribed, do not take the medication in larger quantities.Before to take Clomid notify your doctor if you have ever had any allergic reaction to clomiphene, liver diseases, mental depression, thrombophlebitis.

This drug may cause vision problems, dizziness, or lightheadedness, be especially attentive if you need driving or operating machinery which requires high concentration of attention.

Together with allergy symptoms such as swelling of lips, tongue, or face or hives in some patients may appear the following conditions: ovarian enlargement presenting as abdominal or pelvic pain, flushing, nausea, vomiting, or diarrhea, blurred vision, headache, abnormal uterine bleeding.

Other popular medications in this category are FOSAMAX and PARLODEL

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Filed under: Women's Health


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