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Endep belongs to the tricyclic antidepressants. The drug is mostly used to treat depression and obsessive compulsive disorder (OCD). The last is a nervous condition where a person has recurring thoughts or ideas, or does repetitive things because they are anxious.

Endep works on the central nervous system (CNS) and helps to relieve the symptoms of OCD. The medication helps to restore the balance of certain natural substances (serotonin, among others) in the brain.

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This medication is also used to treat panic attacks and ongoing pain. Take the drug only as prescribed because dosage and schedule may vary on your condition and other factors.

  • It is advised to follow the doctor's instructions carefully and not to take more or less medication than prescribed.
  • It is advised not to eat grapefruit or drink grapefruit juice ( it influences the level of cyclosporin in your blood ). Also limit alcoholic beverages.

Do not suddenly stop taking this medication as your condition may become worse.It may take 2 to 3 weeks or longer before you notice the effects of this medication. Inform your doctor about your condition.

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Inform your doctor or pharmacist if you have certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG). In patients with seizures Endep may cause them more severe. Cautiousness should be exercised in patients with glaucoma and prostate enlargement.

You may feel dizzy or drowsy or have temporary blurred vision. Avoid driving, using machinery, or doing any activity that requires alertness.

Aged people may be more sensitive to the side effects of the drug.During pregnancy this medication should be used only if benefits of its use prevail over potential risk for mother and baby.

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Consult your doctor about the risks.This medicine passes into breast milk so it may cause harm to a nursing infant. It is better to stop breast-feeding while using this drug.Avoid taking Endep with:

  • MAO inhibitors: Furazolidone, Isocarboxazid, Linezolid, Moclobemide Tranylcypromine, etc which cause high fever and convulsions if they are used together with Endep.
  • anti-arrhythmic medication: Propafenone, Quinidine, etc.
  • Epinephrine (stimulates alpha and beta receptors) concomitantly administered with Endep causes severe high blood pressure.
  • Selective Serotonin Reuptake Inhibitors (SSRIs): Citalopram, Dapoxetine, Fluoxetine, Fluvoxamine, Paroxetine, etc.
  • Antipsychotics (also called neuroleptics): Fluphenazine, etc.
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H2-receptor antagonists: Cimetidine, Ranitidine, Famotidine, Nizatidine, etc.

We also advise you to purchase these medications: VENLOR and DESYREL

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